No, that's identifying the Zotero setup that runs on each update, not a file in storage. You can try re-downloading and re-installing the Zotero beta from the official site, but the download channels are well secured and this is almost certainly a false positive (it's detecting what it thinks is the signature of a decade old Trojan)

Now I have a bigger problem. Kaspersky is removing the beta installation file every time I load it. What can I do?

Setting the exclusions did nothing. It was still killing the setup file within a few seconds of it being written to my Downloads folder. I turned off virus protection (not happy to do that), and it let the file stay, but I got a series of errors when I tried to run the executable:

This one from Windows:
https://1drv.ms/i/s!Ak4-SrsRK665gpBk7hKdkIAMYhWzug?e=8MgM3s

This was from Kaspersky:
https://1drv.ms/i/s!Ak4-SrsRK665gpBlypNvIB5OnDulGg?e=oAtHKj

Then I right-clicked on the setup executable in Downloads and found this notice from Kaspersky about the file:
https://1drv.ms/i/s!Ak4-SrsRK665gpBmyRBkzwbOF10HMg?e=0eNWdc

I don't know if the file successfully updated to Zotero because I had already installed it last night. I also looked at information Zotero had about this particular Trojan and it said it was a 2016 Trojan that is still spreading.

I am especially concerned that Windows is also hitting a problem with it.

Thanks, @dstillman. I hope it's a one-time issue.