Word Zotero Buttons not responding

Hello, I installed Zotero without error message but if I click on any Zotero Button in the word menu bar, windows goes gray in nothing pops up. There is also no hidden window (I checked alt+tab etc). When zotero is not running I get the error message, that zotero is not running. But if zotero is running, nothing happens. I already uninstalled zotero and deleted the dotm file from the startup manually, but after a new installation I have the same problem.
I have Windows 11, office 365, a MS Surface 8 Pro and the most current zotero version (reinstalled today)

Please help and thank you in advance.
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