NIS 2009 toolbar
At least on my machine (XP, Zotero 1.07, Firefox 3.04), I've discovered that if I install the Norton Internet Security 2009 Toolbar (which identifies phishing sites and facilitates automated logins) Zotero is unable to save citations, even when it shows a compatible catalog. Thus, for Hollis, if if I have the toolbar installed, I get the translator issue, can't save error message. Uninstall the Norton add-in, and everything works fine.