Help with operation error message, cannot access Zotero on MacOS

I can't access Zotero on my desktop anymore. I tried uninstalling and installing it again, but that didn't help.
This is the message I see:

OperationError: PathUtils.filename: Could not initialize path: NS_ERROR_FILE_UNRECOGNIZED_PATH
isLegacy@chrome://zotero/content/xpcom/dataDirectory.js:659:22
Zotero.DataDirectory.init<@chrome://zotero/content/xpcom/dataDirectory.js:146:18
From previous event:
this.init@chrome://zotero/content/xpcom/zotero.js:273:34
getContentsFromURL@chrome://zotero/content/xpcom/file.js:339:13
Zotero.Intl</<@chrome://zotero/content/xpcom/intl.js:100:35
Zotero.Intl</this.getString@chrome://zotero/content/xpcom/intl.js:144:18
this.getString@chrome://zotero/content/xpcom/zotero.js:1545:24
ZoteroPane<@chrome://zotero/content/zoteroPane.js:3176:19
@chrome://zotero/content/zoteroPane.js:31:18
@chrome://zotero/content/zoteroPane.xhtml:82:25
  • What happened before this started happening?

    Did you set Zotero to use a custom data directory?

    If you go to your Zotero profile folder, open prefs.js with TextEdit, and look for extensions.zotero.dataDir, what's the value?
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