Error on start up

Hi - can anyone help me (or point me to the right page) with this error, please?

Database upgrade error

Error: Error(s) encountered during statement execution: attempt to write a readonly database [QUERY: DELETE FROM itemTypesCombined] [PARAMS: ] [ERROR: attempt to write a readonly database]
Zotero.DBConnection.prototype.queryAsync@chrome://zotero/content/xpcom/db.js:680:13
From previous event:
ZoteroService@file:///C:/Program%20Files%20(x86)/Zotero/components/zotero-service.js:347:7
@chrome://zotero/content/include.js:4:14
  • edited March 23, 2023
    attempt to write a readonly database
    There's a permissions problem with your Zotero data directory or security software on the system is preventing Zotero from writing to it. This is most common if you transferred files from another computer.
  • Thanks - Carbonite had hung, locking it open.
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